BRCAA1 Polyclonal Antibody
Rabbit Anti-BRCAA1 Polyclonal Antibody
Product Specifications
Background
ARID4B encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein (AT-rich interaction domain 4B) is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized.
CAS Number
9007-83-4
Product Name Alternative
ARID4B; BRCAA1; RBBP1L1; RBP1L1; SAP180; AT-rich interactive domain-containing protein 4B; ARID domain-containing protein 4B; 180 kDa Sin3-associated polypeptide; Sin3-associated polypeptide p180; Breast cancer-associated antigen BRCAA1; Hi
Gene ID
51742
Accession Number
Q4LE39
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human BRCAA1
Clonality
Polyclonal
Tag
AT-rich interactive domain-containing protein 4B
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
148kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
BRCAA1 Polyclonal Antibody detects endogenous levels of BRCAA1 protein.
Observed Molecular Weight
148
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Other Product Names
ARID4B; BRCAA1; RBBP1L1; RBP1L1; SAP180; AT-rich interactive domain-containing protein 4B; ARID domain-containing protein 4B; 180 kDa Sin3-associated polypeptide; Sin3-associated polypeptide p180; Breast cancer-associated antigen BRCAA1; Hi
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q4LE39
Isotype
Rabbit IgG
Available Sizes
Curated Selection
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