Blk Polyclonal Antibody

Rabbit Anti-Blk Polyclonal Antibody

Product Specifications

Background

BLK encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein (BLK proto-oncogene, Src family tyrosine kinase) has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors.

CAS Number

9007-83-4

Product Name Alternative

BLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk

Gene ID

640

Accession Number

P51451

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human Blk around the non-phosphorylation site of Y501

Clonality

Polyclonal

Tag

Tyrosine-protein kinase Blk

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

58kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Blk Polyclonal Antibody detects endogenous levels of Blk protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200