TP receptor antagonist-2
Product Specifications
UNSPSC Description
TP receptor antagonist-2 (example 7n) is a thromboxane A2 receptor (TP receptor) antagonist, with IC50 values of 5.64 and 5.27 μM for TPα and TPβ, respectively. TP receptor antagonist-2 inhibits platelet aggregation[1].
Target Antigen
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tp-receptor-antagonist-2.html
Solubility
10 mM in DMSO
Smiles
CC(C)(NC(NS(=O)(C1=C(OC2=CC=C(Cl)C=C2)C=CC(C#N)=C1)=O)=O)C
Molecular Weight
407.87
References & Citations
[1]Bambi-Nyanguile SM, et al. Synthesis and pharmacological evaluation of 2-aryloxy/arylamino-5-cyanobenzenesulfonylureas as novel thromboxane A₂ receptor antagonists. Eur J Med Chem. 2013 Jul;65:32-40.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-160664/TP-receptor-antagonist-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-160664/
Clinical Information
No Development Reported
CAS Number
1448452-22-9
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
