ARHGEF10 Polyclonal Antibody

Rabbit Anti-ARHGEF10 Polyclonal Antibody

Product Specifications

Background

ARHGEF10 encodes a Rho guanine nucleotide exchange factor (GEF) . Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in ARHGEF10 are associated with slowed nerve conduction velocity (SNCV) . Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

ARHGEF10; KIAA0294; Rho guanine nucleotide exchange factor 10

Gene ID

9639

Accession Number

O15013

Reactivity

Human, Monkey

Immunogen

Synthesized peptide derived from the Internal region of human ARHGEF10 at AA range: 310-390

Clonality

Polyclonal

Tag

Rho guanine nucleotide exchange factor 10

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

152kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

ARHGEF10 Polyclonal Antibody detects endogenous levels of ARHGEF10 protein.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200