ANKRD30A Polyclonal Antibody

Rabbit Anti-ANKRD30A Polyclonal Antibody

Product Specifications

Background

Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD30A (ankyrin repeat domain 30A), also known as serologically defined breast cancer antigen NY-BR-1, is a 1,397 amino acid coiled-coil protein. Containing six ANK repeats and thirty-seven exons, ANKRD30A is a distant homolog of the POTE family. Initiated by either Dnmt1 or Met-57, ANKRD30A is highly expressed in breast and testis, and faintly in placenta. Present in 80% of breast cancers, but not in other types of tumors, ANKRD30A is a differentiation antigen and a potential target for antibody‐based therapies in breast cancers.

Product Name Alternative

ANKRD30A; Ankyrin repeat domain-containing protein 30A; Serologically defined breast cancer antigen NY-BR-1

Gene ID

91074

Accession Number

Q9BXX3

Reactivity

Human

Immunogen

Synthesized peptide derived from the C-terminal region of human ANKRD30A at AA range: 1010-1090

Clonality

Polyclonal

Tag

Ankyrin repeat domain-containing protein 30A

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

153kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

ANKRD30A Polyclonal Antibody detects endogenous levels of ANKRD30A protein.

Product Datasheet

https://www.abbkine.com/datasheet/ABP50654.pdf

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200

Other Product Names

ANKRD30A; Ankyrin repeat domain-containing protein 30A; Serologically defined breast cancer antigen NY-BR-1

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q9BXX3

CAS Number

9007-83-4

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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