Amphiphysin I Polyclonal Antibody

Rabbit Anti-Amphiphysin I Polyclonal Antibody

Product Specifications

Background

AMPH encodes a protein (amphiphysin) associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of AMPH is found on chromosome 11.

CAS Number

9007-83-4

Product Name Alternative

AMPH; AMPH1; Amphiphysin

Gene ID

273

Accession Number

P49418

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human Amphiphysin I at AA range: 100-180

Clonality

Polyclonal

Tag

Amphiphysin

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

76kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Amphiphysin I Polyclonal Antibody detects endogenous levels of Amphiphysin I protein.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.