AChRα5 Polyclonal Antibody

Rabbit Anti-AChRα5 Polyclonal Antibody

Product Specifications

Background

Cholinergic receptor nicotinic alpha 5 subunit encoded by CHRNA5 is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2) .

CAS Number

9007-83-4

Product Name Alternative

CHRNA5; NACHRA5; Neuronal acetylcholine receptor subunit alpha-5

Gene ID

1138

Accession Number

P30532

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Synthesized peptide derived from the Internal region of human AChRα5

Clonality

Polyclonal

Tag

Neuronal acetylcholine receptor subunit alpha-5

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

53kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

AChRα5 Polyclonal Antibody detects endogenous levels of AChRα5 protein.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.