Tensin-1 (phospho Tyr1326) Polyclonal Antibody

Rabbit Anti-Tensin-1 (phospho Tyr1326) Polyclonal Antibody

Product Specifications

Background

Tensin 1 encoded by TNS1 localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. Tensin 1 is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms.

CAS Number

9007-83-4

Product Name Alternative

TNS1; TNS; Tensin-1

Gene ID

7145

Accession Number

Q9HBL0

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human Tensin-1 around the phosphorylation site of Y1326

Clonality

Polyclonal

Tag

Tensin-1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

185kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-Tensin-1 (Y1326) Polyclonal Antibody detects endogenous levels of Tensin-1 protein only when phosphorylated at Y1326.

Observed Molecular Weight

185

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.