MEF-2 (phospho Ser408) Polyclonal Antibody

Rabbit Anti-MEF-2 (phospho Ser408) Polyclonal Antibody

Product Specifications

Background

Myocyte enhancer factor 2A encoded by MEF2A is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. Myocyte enhancer factor 2A can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in MEF2A could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1) . Several transcript variants encoding different isoforms have been found for MEF2A.

CAS Number

9007-83-4

Product Name Alternative

MEF2A; MEF2; Myocyte-specific enhancer factor 2A; Serum response factor-like protein 1

Gene ID

4205

Accession Number

Q02078

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human MEF-2 around the phosphorylation site of S408

Clonality

Polyclonal

Tag

Myocyte-specific enhancer factor 2A

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

55kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-MEF-2 (S408) Polyclonal Antibody detects endogenous levels of MEF-2 protein only when phosphorylated at S408.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.