Integrin β3 (phospho Tyr785) Polyclonal Antibody

Rabbit Anti-Integrin β3 (phospho Tyr785) Polyclonal Antibody

Product Specifications

Background

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

CAS Number

9007-83-4

Product Name Alternative

ITGB3; GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD antigen CD61

Gene ID

3690

Accession Number

P05106

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human Integrin β3 around the phosphorylation site of Y785

Clonality

Polyclonal

Tag

Integrin beta-3

Applications

IF, ELISA, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

87kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-Integrin β3 (Y785) Polyclonal Antibody detects endogenous levels of Integrin β3 protein only when phosphorylated at Y785.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF/ICC1:50-300; ELISA 1:2000-20000; IHC 1:50-200