Naringenin chalcone
Product Specifications
UNSPSC Description
Naringenin chalcone is an intermediate in flavonol biosynthesis and is spontaneously metabolized into naringenin (NAR) by chalcone isomerase. Naringenin chalcone is an orally active anti-inflammatory and antiallergic agent[1].
Target Antigen
Others
Type
Natural Products
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/naringenin-chalcone.html
Purity
99.29
Solubility
DMSO : 50 mg/mL (ultrasonic)|Methanol : ≥ 25 mg/mL
Smiles
OC(C=C1)=CC=C1/C=C/C(C2=C(C=C(O)C=C2O)O)=O
Molecular Weight
272.25
References & Citations
[1]Escribano-Ferrer E, et al. In Vivo Anti-inflammatory and Antiallergic Activity of Pure Naringenin, Naringenin Chalcone, and Quercetin in Mice.J Nat Prod. 2019 Feb 22;82(2):177-182.|[2]Iwamura C, Shinoda K, Yoshimura M, Watanabe Y, Obata A, Nakayama T. Naringenin chalcone suppresses allergic asthma by inhibiting the type-2 function of CD4 T cells. Allergol Int. 2010;59(1):67-73. |[3]Hirai S, Kim YI, Goto T, et al. Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages. Life Sci. 2007;81(16):1272-1279.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N3007/Naringenin-chalcone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N3007/Naringenin-chalcone-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
73692-50-9
Available Sizes
Curated Selection
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