HSP70 (Acetyl Lys246) Polyclonal Antibody

Rabbit Anti-HSP70 (Acetyl Lys246) Polyclonal Antibody

Product Specifications

Background

HSPA1A encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, heat shock protein family A (Hsp70) member 1A stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. HSPA1A is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

CAS Number

9007-83-4

Product Name Alternative

HSPA1A; HSPA1; HSPA1B; Heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2

Gene ID

3303/3304

Accession Number

P08107

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human HSP70 around the acetylation site of K246

Clonality

Polyclonal

Tag

Heat shock 70 kDa protein 1A

Applications

WB, ELISA

Field of Research

Cancer#Signal Transduction

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

70kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Acetyl-HSP70 (K246) Polyclonal Antibody detects endogenous levels of HSP70 protein only when non-acetylation at K246.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.