Neuraminidase-IN-21
Neuraminidase-IN-21 (Compound 6d) is an influenza H1N1 virus Neuraminidase inhibitor, with IC50s of 0.30 µM for Neuraminidase, and 30.01 µM for H1N1 strain of influenza. Neuraminidase-IN-21 formsg three hydrogen bonds with Arg292, Arg371, and Tyr406 of Neuraminidase[1].
Product Specifications
UNSPSC
12352101
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/neuraminidase-in-21.html
Smiles
ClC1=CC=C2C(N=CC=C2N/N=C(C3=C(C)N(C4=CC=C(Cl)C=C4)N=N3)\C)=C1
Molecular Formula
C20H16Cl2N6
Molecular Weight
411.29
References & Citations
[1]Sabt A, et al. Discovery of new quinoline derivatives bearing 1-aryl-1,2,3-triazole motif as influenza H1N1 virus neuraminidase inhibitors. Bioorg Chem. 2024 Aug 6;151:107703.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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