Cleaved-COL3A1 (G1221) Polyclonal Antibody

Rabbit Anti-Cleaved-COL3A1 (G1221) Polyclonal Antibody

Product Specifications

Background

COL3A1 encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in COL3A1 are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for COL3A1.

CAS Number

9007-83-4

Product Name Alternative

COL3A1; Collagen alpha-1 (III) chain

Gene ID

1281

Accession Number

P02461

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the C-terminal region of human COL3A1 at AA range: 1140-1220

Clonality

Polyclonal

Tag

Collagen alpha-1 (III) chain

Applications

ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

95kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Cleaved-COL3A1 (G1221) Polyclonal Antibody detects endogenous levels of fragment of activated COL3A1 protein resulting from cleavage adjacent to G1221.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: ELISA 1:10000; Not yet tested in other applications.