Cleaved-Cathepsin L2 (L114) Polyclonal Antibody

Rabbit Anti-Cleaved-Cathepsin L2 (L114) Polyclonal Antibody

Product Specifications

Background

Cathepsin V encoded by CTSV, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. CTSV is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for CTSV in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified.

CAS Number

9007-83-4

Product Name Alternative

CTSL2; CATL2; CTSU; CTSV; Cathepsin L2; Cathepsin U; Cathepsin V

Gene ID

1515

Accession Number

O60911

Reactivity

Human, Monkey

Immunogen

Synthesized peptide derived from the Internal region of human Cathepsin L2 at AA range: 70-150

Clonality

Polyclonal

Tag

Cathepsin L2

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

37kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Cleaved-Cathepsin L2 (L114) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin L2 protein resulting from cleavage adjacent to L114.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.