Cathepsin H Polyclonal Antibody

Rabbit Anti-Cathepsin H Polyclonal Antibody

Product Specifications

Background

The protein encoded by CTSH is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein (cathepsin H), which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of CTSH has been correlated with malignant progression of prostate tumors. Alternate splicing of CTSH results in multiple transcript variants encoding different isoforms.

CAS Number

9007-83-4

Product Name Alternative

CTSH; CPSB; Pro-cathepsin H

Gene ID

1512

Accession Number

P09668

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human Cathepsin H at AA range: 70-150

Clonality

Polyclonal

Tag

Pro-cathepsin H

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

40kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Cathepsin H Polyclonal Antibody detects endogenous levels of Cathepsin H protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; IF 1:50-200