Cleaved-C1s HC (R437) Polyclonal Antibody

Rabbit Anti-Cleaved-C1s HC (R437) Polyclonal Antibody

Product Specifications

Background

C1S encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in C1S are the cause of selective C1s deficiency.

CAS Number

9007-83-4

Product Name Alternative

C1S; Complement C1s subcomponent; C1 esterase; Complement component 1 subcomponent s

Gene ID

716

Accession Number

P09871

Reactivity

Human, Rat

Immunogen

Synthesized peptide derived from the Internal region of human C1s HC at AA range: 360-440

Clonality

Polyclonal

Tag

Complement C1s subcomponent

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

47kD,76kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Cleaved-C1s HC (R437) Polyclonal Antibody detects endogenous levels of fragment of activated C1s HC protein resulting from cleavage adjacent to R437.

Observed Molecular Weight

47+76

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.