Hypophyllanthin (Standard)
Hypophyllanthin (Standard) is the analytical standard of Hypophyllanthin. This product is intended for research and analytical applications. Hypophyllanthin is a major lignan in Phyllanthus spp, with strong anti-inflammatory activity. Hypophyllanthin directly inhibits P-glycoprotein (P-gp) activity and did not interfere with multidrug resistance protein 2 (MRP2) activity[1][2].
Product Specifications
CAS Number
33676-00-5
UNSPSC
12352005
Target
P-glycoprotein; Reference Standards
Type
Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hypophyllanthin-standard.html
Smiles
COC[C@@H]1[C@@H](COC)CC2=CC(OC)=C(OCO3)C3=C2[C@H]1C4=CC=C(OC)C(OC)=C4
Molecular Formula
C24H30O7
Molecular Weight
430.49
References & Citations
[1]Harikrishnan H, et al. Anti-Inflammatory Effects of Hypophyllanthin and Niranthin Through Downregulation of NF-κB/MAPKs/PI3K-Akt Signaling Pathways. Inflammation. 2018 Jun;41 (3) :984-995.|[2]Sukhaphirom N, et al. Phyllanthin and hypophyllanthin inhibit function of P-gp but not MRP2 in Caco-2 cells. J Pharm Pharmacol. 2013 Feb;65 (2) :292-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV771129 1.0 µg DNA
MRPS21P5 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)
Sign In for Pricing
View Details 
![Rabbit Monoclonal GIF Antibody (012) [PE]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
abx658136-01 10 µg
Mouse Mucin 3A, Cell Surface Associated (MUC3A) Protein
Sign In for Pricing
View Details