TLR3, Mouse (sf9, His)

TLR3 protein is an important component of innate and adaptive immunity and can recognize pathogen-associated molecular patterns and activate NF-κ-B, IRF3 and cytokine secretion. Ligand binding induces TLR3 dimerization, and efficient signal transduction requires clustering of signaling units along the ligand. TLR3 Protein, Mouse (sf9, His) is the recombinant mouse-derived TLR3 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of TLR3 Protein, Mouse (sf9, His) is 677 a.a., with molecular weight of 75-80 kDa.