CD4 Monoclonal Antibody

Mouse Anti-CD4 Monoclonal Antibody

Product Specifications

Background

CD4 encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. CD4 is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. CD4 molecule functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in CD4 .

CAS Number

9007-83-4

Product Name Alternative

CD4; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; CD4

Gene ID

920

Accession Number

P01730

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic Peptide

Clonality

Monoclonal

Tag

T-cell surface glycoprotein CD4

Applications

IHC

Purification Method

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous CD4 proteins.

Formulation

Liquid solution

Buffer pH

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:200

Other Product Names

CD4; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; CD4

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Mouse

Accession Number URL

http://www.uniprot.org/uniprot/P01730

Isotype

Mouse IgG1

Available Sizes

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