Tulobuterol

Tulobuterol (C-78 free base) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength[1].

Product Specifications

CAS Number

[41570-61-0]

Product Name Alternative

C-78 (free base)

UNSPSC

12352005

Hazard Statement

H302

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Inflammation/Immunology; Endocrinology

Assay Protocol

https://www.medchemexpress.com/tulobuterol.html

Purity

99.91

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)(NCC(O)C1=CC=CC=C1Cl)C

Molecular Formula

C12H18ClNO

Molecular Weight

227.74

Precautions

H302

References & Citations

[1]Yamaya M, et al. Tulobuterol inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells. Physiol Rep. 2013 Aug;1 (3) :e00041.|[2]Shindoh C, et al. Tulobuterol patch maintains diaphragm muscle contractility for over twenty-four hours in a mouse model of sepsis. Tohoku J Exp Med. 2009 Aug;218 (4) :271-8.