DERL1 rabbit pAb
Derlin 1 (DERL1) Homo sapiens The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012],
Product Specifications
Background
UniProt
Q9BUN8
Swiss Prot
Q9BUN8
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
DERL1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
27kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
27kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Gene ID (Human)
79139
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
PANK1 CRISPR All-in-one AAV vector set (with saCas9)(Rat)
LOC100362110 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
