OPA1 rabbit pAb
This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],
Product Specifications
Background
This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
UniProt
O60313
Swiss Prot
O60313
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from part region of human protein
Target
OPA1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
105kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
105kD
Fragment
IgG
Subcellular Location
Mitochondrion inner membrane ; Single-pass membrane protein . Mitochondrion intermembrane space . Mitochondrion membrane . Detected at contact sites between endoplasmic reticulum and mitochondrion membranes. .
Gene ID (Human)
4976
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
R2142h 1 Each
Human GHRL / Appetite-regulating hormone Recombinant Protein
Sign In for Pricing
View Details LV684270 1.0 µg DNA
CDKN1A Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)
Sign In for Pricing
View Details orb3165605 100 µg
DnaJ homolog subfamily C member 7 Antibody (Fluoro647)
Sign In for Pricing
View Details