Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

DVL1 rabbit pAb

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. [provided by RefSeq, Jul 2008],

Product Specifications

Background

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. [provided by RefSeq, Jul 2008]

Gene ID

1855

UniProt

O14640

Cellular Locus

Cell membrane ; Peripheral membrane protein ; Cytoplasmic side. Cytoplasm, cytosol. Cytoplasmic vesicle. Localizes at the cell membrane upon interaction with frizzled family members..

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

76kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11836-1.pdf

Observed Molecular Weight

76 kD

Subcellular Location

Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytosol . Cytoplasmic vesicle . Localizes at the cell membrane upon interaction with frizzled family members. .

Gene ID (Human)

1855

SwissProt (Human)

O14640

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

KCNH7 CRISPRa sgRNA lentivector (set of three targets)(Human)
25366121 3 x 1.0μg DNA

KCNH7 CRISPRa sgRNA lentivector (set of three targets)(Human)

Ask
View Details
FITC-Linked Polyclonal Antibody to C-Peptide (CP)
MBS2042485-01 0.1 mL

FITC-Linked Polyclonal Antibody to C-Peptide (CP)

Ask
View Details
FITC-Linked Polyclonal Antibody to C-Peptide (CP)
MBS2042485-02 0.2 mL

FITC-Linked Polyclonal Antibody to C-Peptide (CP)

Ask
View Details
FITC-Linked Polyclonal Antibody to C-Peptide (CP)
MBS2042485-03 0.5 mL

FITC-Linked Polyclonal Antibody to C-Peptide (CP)

Ask
View Details
FITC-Linked Polyclonal Antibody to C-Peptide (CP)
MBS2042485-04 1 mL

FITC-Linked Polyclonal Antibody to C-Peptide (CP)

Ask
View Details
FITC-Linked Polyclonal Antibody to C-Peptide (CP)
MBS2042485-05 5 mL

FITC-Linked Polyclonal Antibody to C-Peptide (CP)

Ask
View Details