TIAM1 rabbit pAb
Function: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. similarity: Belongs to the TIAM family. similarity: Contains 1 DH (DBL-homology) domain. similarity: Contains 1 PDZ (DHR) domain. similarity: Contains 1 PH domain. similarity: Contains 1 RBD (Ras-binding) domain. similarity: Contains 2 PH domains. subunit: Interacts with BAIAP2. tissue specificity: Found in virtually all analyzed tumor cell lines including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.
Product Specifications
Background
Gene ID
7074
UniProt
Q13009
Cellular Locus
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
175kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11819-1.pdf
Observed Molecular Weight
175 kD
Subcellular Location
Gene ID (Human)
7074
SwissProt (Human)
Q13009
Available Sizes
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