Fluocinolone acetonide 3-benzylaniline
Fluocinolone acetonide 3-benzylaniline (Precursor Example 1) is a glucocorticoid receptor agonist-linker conjugate, which can be used for the synthesis of anti-CD40 antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[2166375-81-9]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
Target Protein Ligand-Linker Conjugates
Type
ADC Related
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/fluocinolone-acetonide-3-benzylaniline.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@H](C3)O)([C@@]5(C([C@H](C4)F)=CC(C=C5)=O)C)F)([H])C[C@@]1([H])O[C@@H](C6=CC=C(C=C6)CC7=CC(N)=CC=C7)O2)C)=O
Molecular Formula
C35H37F2NO6
Molecular Weight
605.67
Precautions
H302, H315, H319, H335
References & Citations
[1]Adrian D. H, et al. Anti-cd40 antibody drug conjugates. WO2019106608. 2019-06-06
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Recombinant Salmonella agona UPF0260 protein ycgN (ycgN)
Recombinant Salmonella agona UPF0260 protein ycgN (ycgN)
Recombinant Salmonella agona UPF0260 protein ycgN (ycgN)
Recombinant Salmonella agona UPF0260 protein ycgN (ycgN)