Alginic acid

Alginic acid is a natural polysaccharide, which has been widely concerned and applied due to its excellent water solubility, film formation, biodegradability and biocompatibility. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Alginic acid has an inhibitory effect on histamine release. Anti-anaphylactic and anti-inflammatory properties[1][2][3].

Product Specifications

CAS Number

[9005-32-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Autophagy; Endogenous Metabolite; Histamine Receptor

Type

Natural Products

Related Pathways

Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Endocrinology; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/alginic-acid.html

Purity

97.0

Solubility

H2O : 3.03 mg/mL (ultrasonic; adjust pH to 12 with 1M NaOH)

Smiles

O=C(O)[C@@H]1[C@@H](OC)[C@H](O)[C@H](O)[C@H](O[C@H]2[C@H](O)[C@H](O)[C@@H](O[C@H]2C(O)=O)OC)O1.[n]

Molecular Weight

546.39

Precautions

H302, H315, H319, H335

References & Citations

[1]Guo X, et al. Structures, properties and application of alginic acid: A review. Int J Biol Macromol. 2020;162:618-628. |[2]Cui J, et al. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Toxicology. 2022;467:153099.|[3]Jeong HJ, et al. Alginic acid has anti-anaphylactic effects and inhibits inflammatory cytokine expression via suppression of nuclear factor-kappaB activation. Clin Exp Allergy. 2006;36 (6) :785-794.