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GPR6 rabbit pAb

Function: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. similarity: Belongs to the G-protein coupled receptor 1 family.

Product Specifications

Background

Function:Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P) . S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system., similarity:Belongs to the G-protein coupled receptor 1 family.

Gene ID

2830

UniProt

P46095

Cellular Locus

Cell membrane ; Multi-pass membrane protein. Detected in the intracellular compartments. It is currently unclear whether this is a cell surface or intracellular receptor.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human protein . at AA range: 290-370

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

39kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11476-1.pdf

Observed Molecular Weight

39 kD

Subcellular Location

Cell membrane ; Multi-pass membrane protein . Detected in the intracellular compartments. It is currently unclear whether this is a cell surface or intracellular receptor.

Gene ID (Human)

2830

SwissProt (Human)

P46095

Available Sizes

Curated Selection

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