FPR2 rabbit pAb
Function: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). similarity: Belongs to the G-protein coupled receptor 1 family. tissue specificity: Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis.
Product Specifications
Background
Gene ID
2358
UniProt
P25090
Cellular Locus
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,Swine
Reactivity
Human; Rat; Mouse; ; Swine
Immunogen
Synthesized peptide derived from human protein . at AA range: 130-210
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
38kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11464-1.pdf
Observed Molecular Weight
38 kD
Subcellular Location
Gene ID (Human)
2358
SwissProt (Human)
P25090
Available Sizes
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