DHX58 rabbit pAb
Function: Negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA. similarity: Belongs to the helicase family. similarity: Contains 1 helicase ATP-binding domain. similarity: Contains 1 helicase C-terminal domain. subunit: Interacts with DDX58 and probably blocks its homomultimerization.
Product Specifications
Background
Function:Negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA., similarity:Belongs to the helicase family., similarity:Contains 1 helicase ATP-binding domain., similarity:Contains 1 helicase C-terminal domain., subunit:Interacts with DDX58 and probably blocks its homomultimerization.
UniProt
Q96C10
Swiss Prot
Q96C10
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 451-500
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
74kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
74kD
Fragment
IgG
Subcellular Location
Cytoplasm .
Gene ID (Human)
79132
Available Sizes
Curated Selection
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