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OREX rabbit pAb

Hypocretin neuropeptide precursor (HCRT) Homo sapiens This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis. [provided by RefSeq, Jan 2010],

Product Specifications

Background

Hypocretin neuropeptide precursor (HCRT) Homo sapiens This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis. [provided by RefSeq, Jan 2010]

UniProt

O43612

Swiss Prot

O43612

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human protein . at AA range: 21-70

Target

OREX

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

14kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

14kD

Fragment

IgG

Subcellular Location

Rough endoplasmic reticulum . Cytoplasmic vesicle . Cell junction, synapse . Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses. .

Gene ID (Human)

3060

Available Sizes

Curated Selection

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