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ZBP1 rabbit pAb

This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],

Product Specifications

Background

This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Gene ID

81030

UniProt

Q9H171

Cellular Locus

Cytoplasm. Nucleus. Mainly cytoplasmic (PubMed:16876127, PubMed:16990255). Accumulates in the nucleus in response to influenza A virus (IAV) infection: senses IAV defective viral genomes RNA in the nucleus (By similarity)..; [Isoform 7]: Cytoplasm. Nucleus. Compared to isoform 1, a higher proportion of this isoform is localized in the nucleus..

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 21-70

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

47kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11422-1.pdf

Observed Molecular Weight

47 kD

Subcellular Location

Cytoplasm . Nucleus . Mainly cytoplasmic (PubMed:16876127, PubMed:16990255) . Accumulates in the nucleus in response to influenza A virus (IAV) infection: senses IAV defective viral genomes RNA in the nucleus (By similarity) . .; [Isoform 7]: Cytoplasm . Nucleus . Compared to isoform 1, a higher proportion of this isoform is localized in the nucleus. .

Gene ID (Human)

81030

SwissProt (Human)

Q9H171

Available Sizes

Curated Selection

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