RTN2 rabbit pAb

This gene belongs to the family of reticulon encoding genes. Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport. Alternatively spliced transcript variants encoding different isoforms have been identified. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12. [provided by RefSeq, Apr 2012]

Endoplasmic reticulum membrane ; Multi-pass membrane protein. Sarcoplasmic reticulum membrane ; Multi-pass membrane protein. Cell membrane ; Multi-pass membrane protein. Cell membrane, sarcolemma ; Multi-pass membrane protein. Cell membrane, sarcolemma, T-tubule ; Multi-pass membrane protein. Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, cytoskeleton. Localizes to intermediate filaments in mononucleated myoblasts and to Z lines in mature myotubes..

Endoplasmic reticulum membrane ; Multi-pass membrane protein . Sarcoplasmic reticulum membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma ; Multi-pass membrane protein . Cell membrane, sarcolemma, T-tubule ; Multi-pass membrane protein . Cytoplasm, myofibril, sarcomere, Z line . Cytoplasm, cytoskeleton . Localizes to intermediate filaments in mononucleated myoblasts and to Z lines in mature myotubes. .