SPON1 rabbit pAb
Function: Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity). Major factor for vascular smooth muscle cell. similarity: Contains 1 reelin domain. similarity: Contains 1 spondin domain. similarity: Contains 6 TSP type-1 domains. subunit: Binds to the central extracellular domain of APP and inhibits beta-secretase cleavage of APP. tissue specificity: Highest expression in lung, lower expression in brain, heart, kidney, liver and testis, and lowest expression in pancreas, skeletal muscle and ovary. Not expressed in spleen.
Product Specifications
Background
Gene ID
10418
UniProt
Q9HCB6
Cellular Locus
Secreted, extracellular space, extracellular matrix.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 210-290
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
88kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11354-1.pdf
Observed Molecular Weight
88 kD
Subcellular Location
Secreted, extracellular space, extracellular matrix .
Gene ID (Human)
10418
SwissProt (Human)
Q9HCB6
Available Sizes
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