BACE2 rabbit pAb
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Product Specifications
Background
Gene ID
25825
UniProt
Q9Y5Z0
Cellular Locus
Cell membrane ; Single-pass type I membrane protein. Golgi apparatus. Endoplasmic reticulum. Endosome.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 210-290
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
56kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11348-1.pdf
Observed Molecular Weight
56 kD
Subcellular Location
Cell membrane ; Single-pass type I membrane protein . Golgi apparatus . Endoplasmic reticulum. Endosome.
Gene ID (Human)
25825
SwissProt (Human)
Q9Y5Z0
Available Sizes
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