WASL rabbit pAb

This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension. [provided by RefSeq, Jul 2013],

Product Specifications

Background

UniProt

O00401

Swiss Prot

O00401

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 190-270

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

55kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

55kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytoskeleton . Nucleus . Cytoplasm . Preferentially localized in the cytoplasm when phosphorylated and in the nucleus when unphosphorylated (By similarity) . Exported from the nucleus by an nuclear export signal (NES) -dependent mechanism to the cytoplasm (By similarity) . .