SMAGP rabbit pAb

Function: May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation. PTM: O-glycosylated. The O-glycan is modified with sialic acid residues. similarity: Belongs to the SMAGP family. subcellular location: Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions. Detected on cytoplasmic membranes in undifferentiated tumors. tissue specificity: Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level).

Product Specifications

Background

Function:May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation., PTM:O-glycosylated. The O-glycan is modified with sialic acid residues., similarity:Belongs to the SMAGP family., subcellular location:Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions. Detected on cytoplasmic membranes in undifferentiated tumors., tissue specificity:Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level) .

UniProt

Q0VAQ4

Swiss Prot

Q0VAQ4

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 30-110

Target

SMAGP

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

10kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

10kD

Fragment

IgG

Subcellular Location

Cell membrane ; Single-pass type III membrane protein . Cytoplasmic vesicle membrane ; Single-pass type III membrane protein . Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions (PubMed:15021913) . Detected on cytoplasmic membranes in undifferentiated tumors (PubMed:15986429) . .