NALP2 rabbit pAb
NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al. 2003 [PubMed 12563287]). [supplied by OMIM, Mar 2008],
Product Specifications
Background
NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030) . They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]) .[supplied by OMIM, Mar 2008]
UniProt
Q9NX02
Swiss Prot
Q9NX02
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 620-700
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
116kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
116kD
Fragment
IgG
Subcellular Location
Cytoplasm .
Gene ID (Human)
55655
Available Sizes
Curated Selection
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