VMAT2 rabbit pAb
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al. 1993 [PubMed 7905859]). See also SLC18A1 (MIM 193002). [supplied by OMIM, Jan 2011],
Product Specifications
Background
Gene ID
6571
UniProt
Q05940
Cellular Locus
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 1-80
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
56kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11255-1.pdf
Observed Molecular Weight
56 kD
Subcellular Location
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Gene ID (Human)
6571
SwissProt (Human)
Q05940
Available Sizes
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