VMAT2 rabbit pAb
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al. 1993 [PubMed 7905859]). See also SLC18A1 (MIM 193002). [supplied by OMIM, Jan 2011],
Product Specifications
Background
UniProt
Q05940
Swiss Prot
Q05940
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 1-80
Target
VMAT2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
56kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
56kD
Fragment
IgG
Subcellular Location
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Gene ID (Human)
6571
Available Sizes
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