INSRR rabbit pAb
Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. function: This receptor probably binds an insulin related protein and has a tyrosine-protein kinase activity. It phosphorylates the insulin receptor substrates IRS-1 and IRS-2. similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. similarity: Contains 1 protein kinase domain. similarity: Contains 3 fibronectin type-III domains. subunit: Probable tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain.
Product Specifications
Background
Gene ID
3645
UniProt
P14616
Cellular Locus
Membrane; Single-pass type I membrane protein.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 80-160
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
142kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11221-1.pdf
Observed Molecular Weight
142 kD
Subcellular Location
Membrane; Single-pass type I membrane protein.
Gene ID (Human)
3645
SwissProt (Human)
P14616
Available Sizes
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