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LY86 rabbit pAb

Function: May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and Cytokine production. Important for efficient CD180 cell surface expression. induction: In monocytes, down-regulated by the cell-wall fraction of Mycobacterium bovis (BCG-CWS). subcellular location: Associated with CD180 at the cell surface. subunit: Binds CD180. tissue specificity: Highly expressed in B-cells, monocytes and tonsil.

Product Specifications

Background

Function:May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression., induction:In monocytes, down-regulated by the cell-wall fraction of Mycobacterium bovis (BCG-CWS) ., subcellular location:Associated with CD180 at the cell surface., subunit:Binds CD180., tissue specificity:Highly expressed in B-cells, monocytes and tonsil.

Gene ID

9450

UniProt

O95711

Cellular Locus

Secreted, extracellular space. Associated with CD180 at the cell surface.

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 80-160

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

17kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11209-1.pdf

Observed Molecular Weight

17 kD

Subcellular Location

Secreted, extracellular space. Associated with CD180 at the cell surface.

Gene ID (Human)

9450

SwissProt (Human)

O95711

Available Sizes

Curated Selection

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