CRDL2 rabbit pAb
This gene encodes a member of the chordin family of proteins. Chordin family members are secreted proteins that share a cysteine-rich pro-collagen repeat domain and associate with members of the transforming growth factor beta superfamily. In vitro assays demonstrate a direct interaction between the encoded protein and human activin A. This gene is expressed in many tissues including osteoblasts, where it is differentially expressed during differentiation. In addition, its expression is upregulated in human osteoarthritic joint cartilage, suggesting a role in adult cartilage regeneration. [provided by RefSeq, Jan 2015],
Product Specifications
Background
Gene ID
25884
UniProt
Q6WN34
Cellular Locus
[Isoform 1]: Secreted.; [Isoform 2]: Secreted.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm.; [Isoform 5]: Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 330-410
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
47kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11194-1.pdf
Observed Molecular Weight
47 kD
Subcellular Location
[Isoform 1]: Secreted .; [Isoform 2]: Secreted .; [Isoform 3]: Cytoplasm .; [Isoform 4]: Cytoplasm .; [Isoform 5]: Cytoplasm .
Gene ID (Human)
25884
SwissProt (Human)
Q6WN34
Available Sizes
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