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PAR14 rabbit pAb

This gene encodes a member of the poly (ADP-ribose) polymerase (PARP) protein family. The encoded anti-apoptotic protein may regulate aerobic glycolysis and promote survival of cancer cells. Increased expression of this gene has been reported in a variety of tumor types. [provided by RefSeq, Jul 2016],

Product Specifications

Background

This gene encodes a member of the poly (ADP-ribose) polymerase (PARP) protein family. The encoded anti-apoptotic protein may regulate aerobic glycolysis and promote survival of cancer cells. Increased expression of this gene has been reported in a variety of tumor types. [provided by RefSeq, Jul 2016]

Gene ID

54625

UniProt

Q460N5

Cellular Locus

Nucleus. Cytoplasm. In steady state splenocytes the protein is mostly nuclear (By similarity). A minor proportion is detected in the cytoplasm (By similarity). In macrophages, mainly localizes to the cytoplasm (PubMed:27796300)..

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

198kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11162-1.pdf

Observed Molecular Weight

198 kD

Subcellular Location

Nucleus . Cytoplasm . In steady state splenocytes the protein is mostly nuclear (By similarity) . A minor proportion is detected in the cytoplasm (By similarity) . In macrophages, mainly localizes to the cytoplasm (PubMed:27796300) . .

Gene ID (Human)

54625

SwissProt (Human)

Q460N5

Available Sizes

Curated Selection

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