PAR14 rabbit pAb

This gene encodes a member of the poly (ADP-ribose) polymerase (PARP) protein family. The encoded anti-apoptotic protein may regulate aerobic glycolysis and promote survival of cancer cells. Increased expression of this gene has been reported in a variety of tumor types. [provided by RefSeq, Jul 2016],

Product Specifications

Background

UniProt

Q460N5

Swiss Prot

Q460N5

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

198kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

198kD

Fragment

IgG

Subcellular Location

Nucleus . Cytoplasm . In steady state splenocytes the protein is mostly nuclear (By similarity) . A minor proportion is detected in the cytoplasm (By similarity) . In macrophages, mainly localizes to the cytoplasm (PubMed:27796300) . .