DDC rabbit pAb
Dopa decarboxylase (DDC) Homo sapiens The encoded protein catalyzes the decarboxylation of L-3, 4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011],
Product Specifications
Background
Gene ID
1644
UniProt
P20711
Cellular Locus
Cytosol,synaptic vesicle,axon,neuronal cell body,extracellular exosome,
Host
Rabbit
Species Reactivity
Human,Rat,Mouse
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
52kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11130-1.pdf
Observed Molecular Weight
52 kD
Subcellular Location
Cytosol, synaptic vesicle, axon, neuronal cell body, extracellular exosome
Gene ID (Human)
1644
SwissProt (Human)
P20711
Available Sizes
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