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ROBO4 rabbit pAb

Function: Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins. similarity: Belongs to the immunoglobulin superfamily. ROBO family. similarity: Contains 2 fibronectin type-III domains. similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. subunit: Interacts with SLIT2 and ENAH. tissue specificity: Specifically expressed in endothelial cells. Expressed at sites of angiogenesis in different tumor types.

Product Specifications

Background

Function:Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins., similarity:Belongs to the immunoglobulin superfamily. ROBO family., similarity:Contains 2 fibronectin type-III domains., similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains., subunit:Interacts with SLIT2 and ENAH., tissue specificity:Specifically expressed in endothelial cells. Expressed at sites of angiogenesis in different tumor types.

Gene ID

54538

UniProt

Q8WZ75

Cellular Locus

Integral component of membrane,extracellular exosome,

Host

Rabbit

Species Reactivity

Human,Rat,Mouse

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

110kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11129-1.pdf

Observed Molecular Weight

110 kD

Subcellular Location

Integral component of membrane, extracellular exosome

Gene ID (Human)

54538

SwissProt (Human)

Q8WZ75

Available Sizes

Curated Selection

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