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OSCAR rabbit pAb

Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013],

Product Specifications

Background

Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

UniProt

Q8IYS5

Swiss Prot

Q8IYS5

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Target

OSCAR

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

31kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

31kD

Fragment

IgG

Subcellular Location

[Isoform 1]: Secreted .; [Isoform 2]: Cell membrane ; Single-pass type I membrane protein .

Gene ID (Human)

126014

Available Sizes

Curated Selection

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