GPVI rabbit pAb
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
Product Specifications
Background
Gene ID
51206
UniProt
Q9HCN6
Cellular Locus
[Isoform 1]: Cell membrane; Single-pass membrane protein.; [Isoform 2]: Cell membrane; Single-pass membrane protein.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein. AA 21-50
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
55kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11071-1.pdf
Observed Molecular Weight
55 kD
Subcellular Location
[Isoform 1]: Cell membrane; Single-pass membrane protein.; [Isoform 2]: Cell membrane; Single-pass membrane protein.
Gene ID (Human)
51206
SwissProt (Human)
Q9HCN6
Available Sizes
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