DSCAM rabbit pAb

This gene is a member of the immunoglobulin superfamily of cell adhesion molecules (Ig-CAMs), and is involved in human central and peripheral nervous system development. This gene is a candidate for Down syndrome and congenital heart disease (DSCHD). A gene encoding a similar Ig-CAM protein is located on chromosome 11. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012],

Product Specifications

Background

This gene is a member of the immunoglobulin superfamily of cell adhesion molecules (Ig-CAMs), and is involved in human central and peripheral nervous system development. This gene is a candidate for Down syndrome and congenital heart disease (DSCHD) . A gene encoding a similar Ig-CAM protein is located on chromosome 11. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]

UniProt

O60469

Swiss Prot

O60469

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

221kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

221kD

Fragment

IgG

Subcellular Location

[Isoform Short]: Secreted .; [Isoform Long]: Cell membrane ; Single-pass type I membrane protein . Cell projection, axon . Cell projection, dendrite . Cell projection, growth cone . Cell junction, synapse . Localized in the soma, cell membrane, axon and growth cone of dissociated commissural axons. .