TXND2 rabbit pAb
Function: Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase. similarity: Contains 1 thioredoxin domain. subcellular location: In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece. tissue specificity: Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids.
Product Specifications
Background
Gene ID
84203
UniProt
Q86VQ3
Cellular Locus
Cytoplasm. In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
60kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11024-1.pdf
Observed Molecular Weight
60 kD
Subcellular Location
Cytoplasm . In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.
Gene ID (Human)
84203
SwissProt (Human)
Q86VQ3
Available Sizes
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